{"id":1506,"date":"2018-06-14T15:56:05","date_gmt":"2018-06-14T21:56:05","guid":{"rendered":"http:\/\/trinityanimation.com\/blog\/?p=1506"},"modified":"2018-08-10T11:16:29","modified_gmt":"2018-08-10T17:16:29","slug":"mechanism-of-action","status":"publish","type":"post","link":"https:\/\/trinityanimation.com\/blog\/mechanism-of-action\/","title":{"rendered":"Mechanism of Action Pharmacological Animations"},"content":{"rendered":"<p>The term \u201cMechanism of Action,&#8221; as used here, refers to the biochemical process through which a drug produces its effect. Drugs typically bind to receptors, which are located on the surface of cells or within a cell&#8217;s <a href=\"https:\/\/en.wikipedia.org\/wiki\/Cytoplasm\">cytoplasm<\/a> \u2014 a clear semi-solid substance within a cell. Closely related is a term used by some authors: \u201csite of action,\u201d meaning the location in human tissue to which a chemical or drug binds. Some drugs act as an \u201cagonists\u2019 activating the receptors they to which they bind, and, consequently they increase or decrease the activity within the cell. Other drugs, know as as \u201cantagonists\u201d act to block the receptors to which they bind so that natural agonists within the body cannot bind and are, therefore, rendered ineffectual.<\/p>\n<p style=\"text-align: center;\"><iframe loading=\"lazy\" src=\"https:\/\/player.vimeo.com\/video\/256474008\" width=\"640\" height=\"360\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><span data-mce-type=\"bookmark\" style=\"display: inline-block; width: 0px; overflow: hidden; line-height: 0;\" class=\"mce_SELRES_start\">\ufeff<\/span><\/iframe><\/p>\n<p>&nbsp;<\/p>\n<figure id=\"attachment_1507\" aria-describedby=\"caption-attachment-1507\" style=\"width: 306px\" class=\"wp-caption alignleft\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-1507\" src=\"https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_3-2-e1528834374911-300x250.png\" alt=\"This still image is a 3D rendered microscopic elements from one of Trinity's mechanism of action animations. It is an extreme close up shot of a microscopic element demonstrating oxygen diffusing into the blood. This shot displays saturated pinks and purples which visually makes this image more interesting which can impact how the viewer retains the information.\" width=\"306\" height=\"255\" srcset=\"https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_3-2-e1528834374911-300x250.png 300w, https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_3-2-e1528834374911-768x640.png 768w, https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_3-2-e1528834374911-1024x853.png 1024w, https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_3-2-e1528834374911-500x417.png 500w, https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_3-2-e1528834374911-400x333.png 400w, https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_3-2-e1528834374911-1300x1083.png 1300w, https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_3-2-e1528834374911.png 1725w\" sizes=\"auto, (max-width: 306px) 100vw, 306px\" \/><figcaption id=\"caption-attachment-1507\" class=\"wp-caption-text\"><strong>This still image from one of Trinity&#8217;s mechanism of action animations displays the hyper-realism and intriguing color choices of the 3D microscopic elements. This particular shot demonstrates oxygen diffusing into the blood.<\/strong><\/figcaption><\/figure>\n<p>Whether it is a previously approved drug with an unknown mechanism of action, a natural product or a novel molecule identified in the laboratory, researchers seek to understand how a drug or molecule of interest exerts its effects. Once understood, the specific biochemical interaction can be difficult to accurately explain, as the process involves microscopic elements not visible to the naked eye and potentially complex multi-dimensional molecular structures.<\/p>\n<p>&nbsp;<\/p>\n<figure id=\"attachment_1526\" aria-describedby=\"caption-attachment-1526\" style=\"width: 299px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-1526\" src=\"https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_4-2-e1528834467410-300x245.png\" alt=\"This image displays a 3D rendered, detailed, and unique shape representing a microscopic element modeled by Trinity Animators from one of the mechanism of action animations.\" width=\"299\" height=\"244\" srcset=\"https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_4-2-e1528834467410-300x245.png 300w, https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_4-2-e1528834467410-768x627.png 768w, https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_4-2-e1528834467410-1024x835.png 1024w, https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_4-2-e1528834467410-500x408.png 500w, https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_4-2-e1528834467410-400x326.png 400w, https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_4-2-e1528834467410-1300x1061.png 1300w, https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_4-2-e1528834467410.png 1738w\" sizes=\"auto, (max-width: 299px) 100vw, 299px\" \/><figcaption id=\"caption-attachment-1526\" class=\"wp-caption-text\"><strong>Trinity&#8217;s\u00a0 3D hyper-realistic imagery can create unique and complex shapes that represent microscopic elements which provide viewers with better a visualization and understanding of a drug&#8217;s mechanism of action, versus 2D images or diagrams.<\/strong><\/figcaption><\/figure>\n<p>Trinity&#8217;s animators can help clarify your most complicated mechanism of action (MOA) process with a compelling molecular animation. The 3D imagery displays microscopic elements with a unparalleled level of clarity. These pharmaceutical action animations take viewers on an accurately simulated microscopic journey which provides them with a comprehensive view of the drug\u2019s mechanism of action. The same process can be viewed from many different angles, at differing level of enlargement and at different speeds. One of the most important potential uses of a Trinity mechanism of action animation is the submission of an application to a government agency, such as the FDA for approval of a new drug. Once a comprehensive mechanism of action animation has been created it can be re-purposed for patient education materials, as well promotional materials for the medical community. Individual frames of the animation can be selected and rendered at an appropriate resolution for print materials, or for display on a website, or at a medical society gathering.<\/p>\n<figure id=\"attachment_1516\" aria-describedby=\"caption-attachment-1516\" style=\"width: 738px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-1516\" src=\"https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_2-3-300x169.png\" alt=\"This is a very detailed 3D rendered model of a microscopic element displaying the cross-section of bone during bone remodeling from one of Trinity's mechanism of action animations.\" width=\"738\" height=\"416\" srcset=\"https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_2-3-300x169.png 300w, https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_2-3-500x281.png 500w, https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_2-3-400x225.png 400w\" sizes=\"auto, (max-width: 738px) 100vw, 738px\" \/><figcaption id=\"caption-attachment-1516\" class=\"wp-caption-text\"><strong>Many different textures are displayed in this image which Trinity animators paid close attention to in order to produce a hyper-realistic representation of the microscopic elements in their mechanism of action animations.\u00a0 This particular image is the cross-section of bone during bone remodeling.<\/strong><\/figcaption><\/figure>\n<figure id=\"attachment_1563\" aria-describedby=\"caption-attachment-1563\" style=\"width: 737px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-1563\" src=\"https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_7-300x112.png\" alt=\"This image is a 3D rendered microscopic element from one of Trinity's mechanism of action animations.\" width=\"737\" height=\"275\" srcset=\"https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_7-300x112.png 300w, https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_7-768x286.png 768w, https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_7-1024x382.png 1024w, https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_7-500x186.png 500w, https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_7-400x149.png 400w, https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_7-1300x485.png 1300w, https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_7.png 1920w\" sizes=\"auto, (max-width: 737px) 100vw, 737px\" \/><figcaption id=\"caption-attachment-1563\" class=\"wp-caption-text\"><strong>Microscopic elements are detailed and complex shapes, like the image displayed above. Trinity&#8217;s hyper-realistic 3D animations are able to produce the details and textures of the microscopic elements which provide\u00a0viewers with a better understanding when explaining complex concepts such as a drug&#8217;s mechanism of action.<\/strong><\/figcaption><\/figure>\n<p>Trinity\u2019s mechanism of action (MOA) sample reel is a compilation of several original source animations covering different biochemical phenomenon. The compilation gives the viewers an idea of the broad range of micro-level subjects that can be explained through the power of 3D medical animations by Trinity Animation.<\/p>\n<p>The final 3D medical animation is beautifully rendered with stunning imagery and smooth motion. They successfully transmit vital information to health care providers about important complex biological processes. Trinity\u2019s 3D medical animations provide the perfect balance of hyper-clarity and unique visuals displaying microscopic and internal organ imagery which explain bio-chemical processes in an impressively effective way. This rare skill allows Trinity to provide clients who need <a href=\"https:\/\/trinityanimation.com\/blog\/biological-animation-cellular-structures\/\">microscopic elements demonstrated through medical animations<\/a> with the highest quality available.<\/p>\n<figure id=\"attachment_1523\" aria-describedby=\"caption-attachment-1523\" style=\"width: 738px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-1523\" src=\"https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_-300x172.png\" alt=\"This image displays a 3D rendered microscopic view of the inside of the leg while demonstrating the flow of creatine from the kidneys to the muscles in one of Trinity's mechanism of action animations.\" width=\"738\" height=\"423\" srcset=\"https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_-300x172.png 300w, https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_-768x441.png 768w, https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_-1024x588.png 1024w, https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_-500x287.png 500w, https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_-400x230.png 400w, https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_-1300x746.png 1300w\" sizes=\"auto, (max-width: 738px) 100vw, 738px\" \/><figcaption id=\"caption-attachment-1523\" class=\"wp-caption-text\"><strong>This image displays the hyper-realistic detail that the 3D animation can provide of the inside of the human body at a microscopic level. This particular image from the mechanism of action animations demonstrates the flow of creatine from the kidneys to the muscles.<\/strong><\/figcaption><\/figure>\n\n\t\t<div class='ta-footer-blog-sc'>\n\t\t\n\t\t\t<div class='ta-footer-blog-left'>\n\t\t\t\t<a href='\/blog\/category\/medical-animation'>\n\t\t\t\t\t<span class='ta-footer-text-01'>See more blog entries about<\/span>\n\t\t\t\t\t<span class='ta-footer-text-02'>Medical Animations<\/span>\n\t\t\t\t<\/a>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t<div class='ta-footer-blog-img'>\n\t\t\t\t<a href='http:\/\/www.trinityanimation.com\/medical-animation'>\n\t\t\t\t\t<video poster='..\/images\/Medical-Poster_01.jpg' preload='auto' width='300' height'200' loop autoplay muted>\n\t\t\t\t\t\t<source src='https:\/\/player.vimeo.com\/external\/154910399.hd.mp4?s=f77a77da69ba8a1240c45a1272f292418ae944a6&profile_id=175' type='video\/mp4' \/>\n\t\t\t\t\t<\/video>\n\t\t\t\t<\/a>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t<div class='ta-footer-blog-right'>\n\t\t\t\t<a href='http:\/\/www.trinityanimation.com\/medical-animation'>\n\t\t\t\t\t<span class='ta-footer-text-03'>View a Full Profile of<\/span>\n\t\t\t\t\t<span class='ta-footer-text-04'>Trinity Animation<\/span>\n\t\t\t\t<\/a>\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n","protected":false},"excerpt":{"rendered":"<p>The term \u201cMechanism of Action,&#8221; as used here, refers to the biochemical process through which a drug produces its effect. Drugs typically bind to receptors, which are located on the surface of cells or within a cell&#8217;s cytoplasm \u2014 a clear semi-solid substance within a cell. Closely related is a term used by some authors: [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":1507,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[70],"tags":[74,77,75,73],"class_list":["post-1506","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medical-animation","tag-3d-animation","tag-cellular","tag-cellular-medical-animation","tag-medical-animation"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Mechanism of Action Pharmacological Animations<\/title>\n<meta name=\"description\" content=\"Learn about different biochemical phenomena. Trinity Animation&#039;s mechanism of action (MOA) compilation reel explores several original source animations.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/trinityanimation.com\/blog\/mechanism-of-action\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Mechanism of Action Pharmacological Animations\" \/>\n<meta property=\"og:description\" content=\"Learn about different biochemical phenomena. Trinity Animation&#039;s mechanism of action (MOA) compilation reel explores several original source animations.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/trinityanimation.com\/blog\/mechanism-of-action\/\" \/>\n<meta property=\"og:site_name\" content=\"Medical, Technical, Marketing and AR Animation | Trinity Animation\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/Trinity-Animation-106946617793\/\" \/>\n<meta property=\"article:published_time\" content=\"2018-06-14T21:56:05+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2018-08-10T17:16:29+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/trinityanimation.com\/blog\/wp-content\/uploads\/2018\/06\/EDIT_3-2-e1528834374911.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1725\" \/>\n\t<meta property=\"og:image:height\" content=\"1437\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Jim Lammers\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jim Lammers\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/trinityanimation.com\\\/blog\\\/mechanism-of-action\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/trinityanimation.com\\\/blog\\\/mechanism-of-action\\\/\"},\"author\":{\"name\":\"Jim Lammers\",\"@id\":\"https:\\\/\\\/trinityanimation.com\\\/blog\\\/#\\\/schema\\\/person\\\/b362f44ebb4b343ebe947b208b984921\"},\"headline\":\"Mechanism of Action Pharmacological Animations\",\"datePublished\":\"2018-06-14T21:56:05+00:00\",\"dateModified\":\"2018-08-10T17:16:29+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/trinityanimation.com\\\/blog\\\/mechanism-of-action\\\/\"},\"wordCount\":732,\"publisher\":{\"@id\":\"https:\\\/\\\/trinityanimation.com\\\/blog\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/trinityanimation.com\\\/blog\\\/mechanism-of-action\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/trinityanimation.com\\\/blog\\\/wp-content\\\/uploads\\\/2018\\\/06\\\/EDIT_3-2-e1528834374911.png\",\"keywords\":[\"3d animation\",\"cellular\",\"cellular medical animation\",\"medical animation\"],\"articleSection\":[\"Medical Animation\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/trinityanimation.com\\\/blog\\\/mechanism-of-action\\\/\",\"url\":\"https:\\\/\\\/trinityanimation.com\\\/blog\\\/mechanism-of-action\\\/\",\"name\":\"Mechanism of Action Pharmacological Animations\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/trinityanimation.com\\\/blog\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/trinityanimation.com\\\/blog\\\/mechanism-of-action\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/trinityanimation.com\\\/blog\\\/mechanism-of-action\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/trinityanimation.com\\\/blog\\\/wp-content\\\/uploads\\\/2018\\\/06\\\/EDIT_3-2-e1528834374911.png\",\"datePublished\":\"2018-06-14T21:56:05+00:00\",\"dateModified\":\"2018-08-10T17:16:29+00:00\",\"description\":\"Learn about different biochemical phenomena. 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